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Lp-PLA2 Antibody / PLA2G7

CAT: 0800-F54313-0.4MLSize: 0.4 mLDry Ice: NoHazardous: No
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CAT#:0800-F54313-0.4MLSize:0.4 mL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
The protein encoded by this gene is a secreted enzyme that catalyzes the degradation of platelet-activating factor to biologically inactive products. Defects in this gene are a cause of platelet-activating factor acetylhydrolase deficiency.
CAS Number
9007-83-4
Specifications
Western blot: 1:500-1:2000, Immunohistochemistry (FFPE) : 1:25, Flow cytometry: 1:25 (1x10e6 cells)
UniProt
Q13093
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 200-228 from the human protein was used as the immunogen for the Lp-PLA2 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, IHC-P, FACS
Purity
Antigen affinity purified
Format
Purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the Lp-PLA2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This Lp-PLA2 antibody is available for research use only.
Storage Conditions
Aliquot the Lp-PLA2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
The stated application concentrations are suggested starting points. Titration of the Lp-PLA2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
IHC testing of FFPE human tonsil tissue with Lp-PLA2 antibody. HIER: steam section in pH6 citrate buffer for 20 min and allow to cool prior to staining.

UniProtKB · Q13093

Platelet-activating factor acetylhydrolase

PAFA_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q13093
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
PLA2G7
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
PAF acetylhydrolase
EC number
3.1.1.47
Processing
Precursor
Secondary accessions
A5HTT5, Q15692, Q5VTT1, Q8IVA2
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Disease

AsthmaDisease variant

PTM

Glycoprotein

Cellular component

HDLLDLSecreted

Molecular function

Hydrolase

Biological process

Lipid degradationLipid metabolismPhospholipid degradationPhospholipid metabolism

Domain

Signal
Product Datasheet
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