PLA2G7 Antibody / Lp-PLA2 / PAFAH
CAT:
800-RQ4597
Size:
100 µg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
PLA2G7 Antibody / Lp-PLA2 / PAFAH
- Description: Lipoprotein-associated phospholipase A2 (Lp-PLA2), also known as platelet-activating factor acetylhydrolase (PAF-AH), is a phospholipase A2 enzyme that in humans is encoded by the PLA2G7 gene. Lp-PLA2 is a 45-50 kDa protein of 441 amino acids. It is one of several PAF acetylhydrolases. In the blood it travels mainly with low-density lipoprotein (LDL). Less than 20% is associated with high-density lipoprotein HDL. It is an enzyme produced by inflammatory cells and hydrolyzes oxidized phospholipids in LDL. Lp-PLA2 is platelet-activating factor (PAF) acetylhydrolase, a secreted enzyme that catalyzes the degradation of PAF to inactive products by hydrolysis of the acetyl group at the sn-2 position, producing the biologically inactive products LYSO-PAF and acetate.
- CAS Number: 9007-83-4
- UniProt: Q13093
- Host: Rabbit
- Immunogen: Amino acids A176-N415 from the human protein were used as the immunogen for the PLA2G7 antibody.
- Clonality: Polyclonal
- Isotype: IgG
- Applications: WB, ELISA (Capture)
- Format: Purified
- Buffer: 0.5mg/ml if reconstituted with 0.2ml sterile DI water
- Reconstitution: After reconstitution, the PLA2G7 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
- Limitations: This PLA2G7 antibody is available for research use only.