INTS3 Antibody

• Description:

  Component of the Integrator complex. The Integrator complex is involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes.

• Specifications:

  Western blot: 1:2000

• UniProt:

  Q68E01

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  Amino acids 1000-1034 from the human protein were used as the immunogen for this INTS3 antibody.

• Clonality:

  Polyclonal

• Isotype:

  Ig

• Applications:

  WB

• Purity:

  Antigen affinity

• Format:

  Antigen affinity purified

• Buffer:

  Antibody in 1X PBS, pH 7.4, with 0.09% sodium azide

• Reconstitution:

  Aliquot the INTS3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

• Limitations:

  This INTS3 antibody is available for research use only.

• Storage Conditions:

  Aliquot the INTS3 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

• Formulation:

  In 1X PBS, pH 7.4, with 0.09% sodium azide

• Applications Notes:

  The stated application concentrations are suggested starting points. Titration of the INTS3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

• CAS Number:

  9007-83-4

• Image Legend:

  Western blot testing of INTS3 antibody at 1:2000 + Lane 1: human 293, 2: HeLa, and 3: Jurkat cell lysate. Predicted molecular weight ~118 kDa.