INTS13 Antibody / Integrator complex subunit 13

• Description :

  Integrator Complex Subunit 13 Protein, also known as INTS13, is a subunit of the Integrator complex, which plays a critical role in the 3' end processing of small nuclear RNAs (snRNAs) . This complex is responsible for the cleavage and polyadenylation of snRNAs, which are essential for the splicing of pre-mRNA. INTS13 is specifically involved in the cleavage step of snRNA processing, highlighting its importance in gene expression regulation.

• Specifications :

  Western blot: 1-2 µg/mL, Immunofluorescence: 5 µg/mL, ELISA: 0.1-0.5 µg/mL

• UniProt :

  Q9NVM9

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  An E.coli-derived human recombinant protein (amino acids M1-H254) was used as the immunogen for the INTS13 antibody.

• Clonality :

  Polyclonal

• Isotype :

  IgG

• Applications :

  WB, IF, ELISA

• Purity :

  Antigen affinity chromatography

• Format :

  Antigen affinity purified

• Buffer :

  Lyophilized from 1X PBS with 2% Trehalose

• Limitations :

  This INTS13 antibody is available for research use only.

• Storage Conditions :

  After reconstitution, the INTS13 Antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

• Formulation :

  0.5 mg/mL if reconstituted with 0.2ml sterile DI water

• Applications Notes :

  Optimal dilution of the INTS13 antibody should be determined by the researcher.

• Location :

  Nuclear, cytoplasmic

• Image Legend :

  Immunofluorescent staining of FFPE human U-2 OS cells with INTS13 antibody (red) and Beta Tubulin mAb (green) . HIER: steam section in pH6 citrate buffer for 20 min.