INTS6 Antibody

• Description:

  Integrator complex subunit 6 is a component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes. May have a tumor suppressor role; an ectopic expression suppressing tumor cell growth.

• Specifications:

  Western blot: 1:1000-2000

• Gene ID:

  26512

• UniProt:

  Q9UL03

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  A portion of amino acids 135-167 from the human protein was used as the immunogen for the INTS6 antibody.

• Clonality:

  Polyclonal

• Isotype:

  Ig

• Applications:

  WB

• Purity:

  Antigen affinity

• Format:

  Antigen affinity purified

• Buffer:

  In 1X PBS, pH 7.4, with 0.09% sodium azide

• Reconstitution:

  Aliquot the INTS6 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

• Limitations:

  This INTS6 antibody is available for research use only.

• Storage Conditions:

  Aliquot the INTS6 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

• Formulation:

  In 1X PBS, pH 7.4, with 0.09% sodium azide

• Applications Notes:

  Titration of the INTS6 antibody may be required due to differences in protocols and substrate sensitivity.

• Prediction Reactivity:

  Mouse

• CAS Number:

  9007-83-4

• Image Legend:

  Western blot testing of human 1) A431 and 2) HeLa cell lysate with INTS6 antibody at 1:2000. Predicted molecular weight: 100 kDa.