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PDS5B Antibody / AS3

CAT: 0800-F53857-0.2MLSize: 0.2 mLDry Ice: NoHazardous: No
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CAT#:0800-F53857-0.2MLSize:0.2 mL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Regulator of sister chromatid cohesion in mitosis which may stabilize cohesin complex association with chromatin. May couple sister chromatid cohesion during mitosis to DNA replication. Cohesion ensures that chromosome partitioning is accurate in both meiotic and mitotic cells and plays an important role in DNA repair. Plays a role in androgen-induced proliferative arrest in prostate cells.
CAS Number
9007-83-4
Specifications
Western blot: 1:1000-2000
UniProt
Q9NTI5
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 1197-1228 from the human protein was used as the immunogen for the PDS5B antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the PDS5B antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This PDS5B antibody is available for research use only.
Storage Conditions
Aliquot the PDS5B antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the PDS5B antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
Western blot testing of human 1) 293T/17, 2) DU-145, 3) LNCaP, 4) Raji, 5) U-2OS and 6) HeLa cell lysate with PDS5B antibody at 1:2000. Predicted molecular weight: 165 kDa.

UniProtKB · Q9NTI5

Sister chromatid cohesion protein PDS5 homolog B

PDS5B_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q9NTI5
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
PDS5B
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
Q5R3S3, Q5W0K8, Q6NSC3, Q8IXT6, Q9H5N8, Q9Y2I5, Q9Y451
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

PTM

AcetylationPhosphoprotein

Coding sequence diversity

Alternative splicing

Biological process

Cell cycleCell divisionMitosis

Cellular component

Nucleus

Domain

Repeat

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