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Insulin Antibody

CAT: 0800-F53596-0.1MLSize: 0.1 mLDry Ice: NoHazardous: No
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CAT#:0800-F53596-0.1MLSize:0.1 mL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. Alternative splicing results in multiple transcript variants. [provided by RefSeq].
CAS Number
9007-83-4
Specifications
Western blot: 1:1000-1:8000
UniProt
P01308
Host
Mouse
Reactivity
Human
Immunogen
A portion of amino acids 35-64 from the human protein was used as the immunogen for this Insulin antibody.
Clonality
Monoclonal
Isotype
IgM
Clone
396CT20.4.4
Applications
WB, ELISA
Purity
Ascites
Format
Ascites
Buffer
In ascites with 0.09% sodium azide
Reconstitution
Aliquot the Insulin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This Insulin antibody is available for research use only.
Storage Conditions
Aliquot the Insulin antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In ascites with 0.09% sodium azide
Applications Notes
Titration of the Insulin antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
Insulin antibody western blot analysis in human CEM cell lysate.

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