P16INK4a Antibody

• Description:

  Acts as a negative regulator of the proliferation of normal cells by interacting strongly with CDK4 and CDK6. This inhibits their ability to interact with cyclins D and to phosphorylate the retinoblastoma protein.

• Specifications:

  Western blot: 1:2000

• UniProt:

  P42771

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This p16INK4a antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 145-176 amino acids from human p16-INK4a.

• Clonality:

  Polyclonal

• Isotype:

  Ig

• Applications:

  WB, ELISA

• Purity:

  Antigen affinity

• Format:

  Antigen affinity purified

• Buffer:

  In 1X PBS, pH 7.4, with 0.09% sodium azide

• Reconstitution:

  Aliquot the p16INK4A antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

• Limitations:

  This p16INK4a antibody is available for research use only.

• Storage Conditions:

  Aliquot the p16INK4a antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

• Formulation:

  In 1X PBS, pH 7.4, with 0.09% sodium azide

• Applications Notes:

  Titration of the p16INK4a antibody may be required due to differences in protocols and secondary/substrate sensitivity.

• CAS Number:

  9007-83-4

• Image Legend:

  Western blot testing of p16INK4a antibody at 1:2000 dilution + HeLa lysate; Predicted molecular weight: 17 kDa.