SOX7 Antibody

• Description :

  Binds to and activates the CDH5 promoter, hence plays a role in the transcriptional regulation of genes expressed in the hemogenic endothelium and blocks further differentiation into blood precursors (By similarity) . May be required for the survival of both hematopoietic and endothelial precursors during specification (By similarity) . Competes with GATA4 for binding and activation of the FGF3 promoter (By similarity) . Represses Wnt/beta-catenin-stimulated transcription, probably by targeting CTNNB1 to proteasomal degradation. Binds the DNA sequence 5'- AACAAT-3'.

• Specifications :

  Western blot: 1:1000

• UniProt :

  Q9BT81

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  A portion of amino acids 224-258 of the human protein was used as the immunogen for the SOX7 antibody.

• Clonality :

  Polyclonal

• Isotype :

  Ig

• Applications :

  WB, ELISA

• Purity :

  Antigen affinity

• Format :

  Antigen affinity purified

• Buffer :

  In 1X PBS, pH 7.4, with 0.09% sodium azide

• Reconstitution :

  Aliquot the SOX7 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

• Limitations :

  This SOX7 antibody is available for research use only.

• Storage Conditions :

  Aliquot the SOX7 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

• Formulation :

  In 1X PBS, pH 7.4, with 0.09% sodium azide

• Applications Notes :

  Titration of the SOX7 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

• CAS Number :

  9007-83-4

• Image Legend :

  Western blot analysis of lysate from human kidney tissue lysate using SOX7 antibody diluted at 1:1000. Predicted molecular weight: 42/49 kDa (isoforms 1/2) .