SOX2 Antibody

CAT: 0800-F52921-0.4MLSize: 0.4 mLDry Ice: NoHazardous: No
CAT#:0800-F52921-0.4MLSize:0.4 mL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206 (By similarity) . Critical for early embryogenesis and for embryonic stem cell pluripotency. May function as a switch in neuronal development. Downstream SRRT target that mediates the promotion of neural stem cell self-renewal (By similarity) . Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation (By similarity) .
CAS Number
9007-83-4
Specifications
Western blot: 1:1000
UniProt
P48431
Host
Rabbit
Reactivity
Human
Immunogen
This SOX2 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 30-63 amino acids from the N-terminal region of human SOX2.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, ELISA
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the SOX2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This SOX2 antibody is available for research use only.
Storage Conditions
Aliquot the SOX2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the SOX2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Location
Cytoplasmic, nuclear
Image Legend
Western blot analysis of lysate from NCCIT cell line using SOX2 antibody at 1:1000.
Product Datasheet
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