CD74 Antibody

• Description:

  Plays a critical role in MHC class II antigen processing by stabilizing peptide-free class II alpha/beta heterodimers in a complex soon after their synthesis and directing transport of the complex from the endoplasmic reticulum to the endosomal/lysosomal system where the antigen processing and binding of antigenic peptides to MHC class II takes place. Serves as cell surface receptor for the cytokine MIF.

• Specifications:

  Flow Cytometry: 1:25, Western blot: 1:1000

• UniProt:

  P04233

• Host:

  Mouse

• Reactivity:

  Human

• Immunogen:

  This CD74 antibody was produced from a mouse immunized with a KLH conjugated synthetic peptide between 1-232 amino acids from human protein.

• Clonality:

  Monoclonal

• Isotype:

  IgG2b κ

• Clone:

  1267CT820.116.140.154

• Applications:

  WB, FACS, ELISA

• Purity:

  Purified

• Format:

  Purified

• Buffer:

  In 1X PBS, pH 7.4, with 0.09% sodium azide

• Reconstitution:

  Aliquot the CD74 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

• Limitations:

  This CD74 antibody is available for research use only.

• Storage Conditions:

  Aliquot the CD74 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

• Formulation:

  In 1X PBS, pH 7.4, with 0.09% sodium azide

• Applications Notes:

  Titration of the CD74 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

• CAS Number:

  9007-83-4

• Image Legend:

  Flow cytometric analysis of Raji cells using CD74 antibody (green) and an isotype control of mouse IgG2b (blue) ; Ab was diluted at 1:25 dilution.