CD86 Antibody

CAT: 0800-F44504-0.08MLSize: 0.08 mLDry Ice: NoHazardous: No
CAT#:0800-F44504-0.08MLSize:0.08 mL
Selected
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in two transcript variants encoding different isoforms. Additional transcript variants have been described, but their full-length sequences have not been determined. [provided by RefSeq].
CAS Number
9007-83-4
Specifications
Western blot: 1:1000
UniProt
P42081
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 269-298 from the human protein was used as the immunogen for this CD86 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, ELISA
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the CD86 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This CD86 antibody is available for research use only.
Storage Conditions
Aliquot the CD86 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the CD86 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
CD86 antibody western blot analysis in NCI-H292 lysate

Popular Products