TLR2 Antibody
CAT:
800-F44371-0.4ML
Size:
0.4 mL
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
TLR2 Antibody
- Description: TLR2 is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. TLR2 is expressed most abundantly in peripheral blood leukocytes, and mediates host response to Gram-positive bacteria and yeast via stimulation of NF-kappaB.
- CAS Number: 9007-83-4
- UniProt: Q9QUN7
- Host: Rabbit
- Immunogen: A portion of amino acids 720-749 from the mouse protein was used as the immunogen for this anti-TLR2 antibody.
- Clonality: Polyclonal
- Isotype: Ig
- Applications: WB, IHC, ELISA
- Format: Purified
- Buffer: In 1X PBS, pH 7.4, with 0.09% sodium azide
- Reconstitution: Aliquot the anti-TLR2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
- Limitations: This anti-TLR2 antibody is available for research use only.