TLR2 Antibody

• Description :

  Cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components. Cooperates with TLR1 or TLR6 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. May also promote apoptosis in response to lipoproteins. Recognizes mycoplasmal macrophage-activating lipopeptide-2kD (MALP-2), soluble tuberculosis factor (STF), phenol-soluble modulin (PSM) and B.burgdorferi outer surface protein A lipoprotein (OspA-L) cooperatively with TLR6. [UniProt]

• Specifications :

  Western blot: 1:500-1:1000

• UniProt :

  O60603

• Host :

  Mouse

• Reactivity :

  Human

• Immunogen :

  Recombinant human TLR2 was used as the immunogen for the TLR2 antibody.

• Clonality :

  Monoclonal

• Isotype :

  IgG1 k

• Clone :

  1070CT4.2.3.2

• Applications :

  WB

• Purity :

  Protein G purified

• Format :

  Purified

• Buffer :

  In 1X PBS, pH 7.4, with 0.09% sodium azide

• Reconstitution :

  Aliquot the TLR2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

• Limitations :

  This TLR2 antibody is available for research use only.

• Storage Conditions :

  Aliquot the TLR2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

• Formulation :

  In 1X PBS, pH 7.4, with 0.09% sodium azide

• Applications Notes :

  The stated application concentrations are suggested starting points. Titration of the TLR2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

• CAS Number :

  9007-83-4

• Image Legend :

  Western blot testing of TLR2 antibody at 1:500: Lane 1) human Ramos, 2) A549 and 3) MDA-MB-231 cell lysate. Predicted molecular weight: 85-90 kDa.