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Oct-2 Antibody / POU2F2

CAT: 0800-F43298-0.4MLSize: 0.4 mLDry Ice: NoHazardous: No
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CAT#:0800-F43298-0.4MLSize:0.4 mL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Oct-2/POU2F2 is a transcription factor that specifically binds to the octamer motif (5'-ATTTGCAT-3') . Regulates transcription in a number of tissues in addition to activating immunoglobulin gene expression. Modulates transcription transactivation by NR3C1, AR and PGR. Isoform 5 activates the U2 small nuclear RNA (snRNA) promoter.
CAS Number
9007-83-4
Specifications
Western blot: 1:1000, IHC (Paraffin) : 1:10-1:50
UniProt
P09086
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 10-39 from the human protein was used as the immunogen for this Oct-2 antibody. This sequence is common to isoforms 1-5.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, IHC, ELISA
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the Oct-2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This Oct-2 antibody is available for research use only.
Storage Conditions
Aliquot the Oct-2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the Oct-2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Prediction Reactivity
Mouse, Pig
Image Legend
Oct-2 antibody western blot analysis in ZR-75-1 lysate. Predicted molecular weight: isoforms 1-5 range in size from 43~62kDa.

UniProtKB · P09086

POU domain, class 2, transcription factor 2

PO2F2_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P09086
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
POU2F2
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
Q16648, Q7M4M8, Q9BRS4
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Molecular function

ActivatorDNA-binding

Coding sequence diversity

Alternative splicing

Cellular component

CytoplasmNucleus

Domain

Homeobox

Biological process

TranscriptionTranscription regulation
Product Datasheet
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