Anti-Oct-2 (H3) POU2F2 Antibody

• Description:

  Boster Bio Anti-Oct-2 (H3) POU2F2 Antibody catalog # A04407-1. Tested in WB, IHC, IF applications. This antibody reacts with Human, Mouse.

• Synonyms:

  POU domain, class 2, transcription factor 2; Lymphoid-restricted immunoglobulin octamer-binding protein NF-A2; Octamer-binding protein 2; Oct-2; Octamer-binding transcription factor 2; OTF-2; POU2F2; OCT2, OTF2;

• Gene Name:

  POU2F2

• UniProt:

  P09086

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  Synthetic peptide, corresponding to the N-terminus of Human Oct-2.

• Clonality:

  Polyclonal

• Tissue Specificity:

  Isoform 3 is B-cell specific. Isoform 5 is expressed in B-cells and the immunoglobulin-expressing T-cell line MOLT-4, but not in the T-cell line BW5147.

• Applications:

  WB, IHC, IF

• Purification:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

• Form:

  Liquid

• Function:

  Transcription factor that specifically binds to the octamer motif (5'-ATTTGCAT-3') . Regulates transcription in a number of tissues in addition to activating immunoglobulin gene expression. Modulates transcription transactivation by NR3C1, AR and PGR. Isoform 5 activates the U2 small nuclear RNA (snRNA) promoter.

• Molecular Weight:

  51209 MW

• Shipping Conditions:

  Available

• Storage Conditions:

  Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

• Other Gene Names:

  POU domain, class 2, transcription factor 2

• Subcellular Location:

  Cytoplasm . Nucleus.

• Protein Name:

  POU domain, class 2, transcription factor 2