RNF8 Antibody

• Description :

  The protein encoded by this gene contains a RING finger motif and a FHA domain. This protein has been shown to interact with several class II ubiquitin-conjugating enzymes (E2), including UBE2E1/UBCH6, UBE2E2, and UBE2E3, and may act as an ubiquitin ligase (E3) in the ubiquitination of certain nuclear proteins. Alternatively spliced transcript variants encoding distinct isoforms have been reported.

• CAS Number :

  9007-83-4

• Specifications :

  Western blot: 1:1000

• UniProt :

  O76064

• Host :

  Rabbit

• Reactivity :

  Human, Mouse

• Immunogen :

  A portion of amino acids 335-364 from the human protein was used as the immunogen for this RNF8 antibody.

• Clonality :

  Polyclonal

• Isotype :

  Ig

• Applications :

  WB, ELISA

• Purity :

  Antigen affinity

• Format :

  Antigen affinity purified

• Buffer :

  In 1X PBS, pH 7.4, with 0.09% sodium azide

• Reconstitution :

  Aliquot the RNF8 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

• Limitations :

  This RNF8 antibody is available for research use only.

• Storage Conditions :

  Aliquot the RNF8 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

• Formulation :

  In 1X PBS, pH 7.4, with 0.09% sodium azide

• Applications Notes :

  Titration of the RNF8 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

• Image Legend :

  RNF8 antibody western blot analysis in CEM lysate. Predicted molecular weight: 55/51 kDa (isoforms 1/3), but may be observed at larger sizes due to ubiquitination.