FOXA2 Antibody

• Description :

  FOXA2 is a transcription factor that is involved in embryonic development, establishment of tissue-specific gene expression and regulation of gene expression in differentiated tissues. Is thought to act as a 'pioneer' factor opening the compacted chromatin for other proteins through interactions with nucleosomal core histones and thereby replacing linker histones at target enhancer and/or promoter sites. [UniProt]

• Specifications :

  Western blot: 1:1000, IHC (Paraffin) : 1:10-1:50, Immunofluorescence: 1:10-1:50

• UniProt :

  Q9Y261

• Host :

  Rabbit

• Reactivity :

  Human, Rat

• Immunogen :

  A portion of amino acids 380-407 from the human protein was used as the immunogen for this FOXA2 antibody.

• Clonality :

  Polyclonal

• Isotype :

  Ig

• Applications :

  IHC, IF, WB, ELISA

• Purity :

  Antigen affinity

• Format :

  Antigen affinity purified

• Buffer :

  In 1X PBS, pH 7.4, with 0.09% sodium azide

• Reconstitution :

  Aliquot the FOXA2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

• Limitations :

  This FOXA2 antibody is available for research use only.

• Storage Conditions :

  Aliquot the FOXA2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

• Formulation :

  In 1X PBS, pH 7.4, with 0.09% sodium azide

• Applications Notes :

  Titration of the FOXA2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

• Prediction Reactivity :

  Mouse

• CAS Number :

  9007-83-4

• Image Legend :

  Confocal immunofluorescent analysis of FOXA2 antibody with HeLa cells followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green) . Actin filaments have been labeled with Alexa Fluor 555 Phalloidin (red) . DAPI was used as a nuclear counterstain (blue) .