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Cyclin C Antibody (CCNC)

CAT: 0800-F41289-0.4MLSize: 0.4 mLDry Ice: NoHazardous: No
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CAT#:0800-F41289-0.4MLSize:0.4 mL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
The protein encoded by this gene is a member of the cyclin family of proteins. The encoded protein interacts with cyclin-dependent kinase 8 and induces the phophorylation of the carboxy-terminal domain of the large subunit of RNA polymerase II. The level of mRNAs for this gene peaks in the G1 phase of the cell cycle. Two transcript variants encoding different isoforms have been found for this gene.
CAS Number
9007-83-4
Specifications
Western blot: 1:1000, Flow Cytometry: 1:10-1:50
UniProt
P24863
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 1-30 from the human protein was used as the immunogen for this Cyclin C antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, FACS, ELISA
Purity
Purified
Format
Purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the Cyclin C antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This Cyclin C antibody is available for research use only.
Storage Conditions
Aliquot the Cyclin C antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the Cyclin C antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
Cyclin C antibody flow cytometric analysis of HeLa cells (right histogram) compared to a negative control (left histogram) . FITC-conjugated goat-anti-rabbit secondary Ab was used for the analysis.

UniProtKB · P24863

Cyclin-C

CCNC_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P24863
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
CCNC
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
B4DPZ1, Q9H543
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Molecular function

ActivatorCyclinRepressor

Coding sequence diversity

Alternative splicing

Cellular component

Nucleus

PTM

Phosphoprotein

Biological process

TranscriptionTranscription regulation

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