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ACN9 Antibody / SDHAF3

CAT: 0800-F41148-0.08MLSize: 0.08 mLDry Ice: NoHazardous: No
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CAT#:0800-F41148-0.08MLSize:0.08 mL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
ACN9/SDHAF3 plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Promotes maturation of the iron-sulfur protein subunit SDHB of the SDH catalytic dimer, protecting it from the deleterious effects of oxidants. May act together with SDHAF1. [UniProt]
CAS Number
9007-83-4
Specifications
Western blot: 1:500-1000, IHC (Paraffin) : 1:50-1:100
UniProt
Q9NRP4
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
A portion of amino acids 13-42 from the human protein was used as the immunogen for this ACN9 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, IHC, ELISA
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the ACN9 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This ACN9 antibody is available for research use only.
Storage Conditions
Aliquot the ACN9 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the ACN9 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Location
Cytoplasmic
Image Legend
ACN9 antibody western blot analysis in mouse bladder tissue lysate. Predicted molecular weight ~15 kDa.

UniProtKB · Q9NRP4

Succinate dehydrogenase assembly factor 3, mitochondrial

SDHF3_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q9NRP4
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
SDHAF3
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
SDH assembly factor 3, SDHAF3
EC number
—
Processing
Precursor
Secondary accessions
A4D1J3, Q75MD6
Protein keywords

Molecular function

Chaperone

Cellular component

Mitochondrion

Technical term

Proteomics identificationReference proteome

Domain

Transit peptide

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