HDAC1 Antibody

• Description :

  Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. HDAC1 belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis.

• Specifications :

  Western blot: 1:1000, Immunofluorescence: 1:10-1:50

• UniProt :

  Q13547

• Host :

  Rabbit

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  A portion of amino acids 1-30 from the human protein was used as the immunogen for this HDAC1 antibody.

• Clonality :

  Polyclonal

• Isotype :

  Ig

• Applications :

  IF, WB, ELISA

• Purity :

  Purified

• Format :

  Purified

• Buffer :

  In 1X PBS, pH 7.4, with 0.09% sodium azide

• Reconstitution :

  Aliquot the HDAC1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

• Limitations :

  This HDAC1 antibody is available for research use only.

• Storage Conditions :

  Aliquot the HDAC1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

• Formulation :

  In 1X PBS, pH 7.4, with 0.09% sodium azide

• Applications Notes :

  Titration of the HDAC1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

• CAS Number :

  9007-83-4

• Image Legend :

  HDAC1 antibody western blot analysis of (1) HeLa, (2) K562, (3) mouse NIH3T3 cell line and (4) mouse testis, (5) rat testis and (6) rat spleen tissue lysate. Predicted molecular weight 55~60 kDa