CD11b Antibody
CAT:
800-F40833-0.08ML
Size:
0.08 mL
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
CD11b Antibody
- Description: CD11b is the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles.
- CAS Number: 9007-83-4
- UniProt: P11215
- Host: Rabbit
- Immunogen: A portion of amino acids 253-282 from the human protein was used as the immunogen for this CD11b antibody.
- Clonality: Polyclonal
- Isotype: Ig
- Applications: IHC, FACS, WB, ELISA
- Format: Antigen affinity purified
- Buffer: In 1X PBS pH 7.4 with 0.09% sodium azide
- Reconstitution: Aliquot the CD11b antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
- Limitations: This CD11b antibody is available for research use only.