CD44 Antibody

• Description :

  The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs) . This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis.

• Specifications :

  Western blot: 1:100-1:500, Immunohistochemistry (FFPE) : 1:10-1:50, Immunofluorescence: 1:10-1:50, Flow cytometry: 1:10-1:50

• UniProt :

  P16070

• Host :

  Mouse

• Reactivity :

  Human

• Immunogen :

  This CD44 antibody was produced from a mouse immunized with recombinant protein.

• Clonality :

  Monoclonal

• Isotype :

  IgG2a κ

• Clone :

  Hermes-3

• Applications :

  WB, IHC-P, IF, FACS

• Purity :

  Purified

• Format :

  Purified

• Buffer :

  In 1X PBS pH 7.4 with 0.09% sodium azide

• Reconstitution :

  Aliquot the CD44 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

• Limitations :

  This CD44 antibody is available for research use only.

• Storage Conditions :

  Aliquot the CD44 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

• Formulation :

  In 1X PBS, pH 7.4, with 0.09% sodium azide

• Applications Notes :

  Titration of the CD44 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

• CAS Number :

  9007-83-4

• Location :

  Cell surface, cytoplasmic

• Image Legend :

  CD44 antibody western blot analysis in HeLa lysate