ERBB4 Antibody

• Description:

  ERBB4 acts as cell-surface receptor for the neuregulins NRG1, NRG2, NRG3 and NRG4 and the EGF family members BTC, EREG and HBEGF. Ligand binding triggers receptor dimerization and autophosphorylation at specific tyrosine residues that then serve as binding sites for scaffold proteins and effectors. [UniProt]

• Specifications:

  Western blot: 1:1000

• UniProt:

  Q15303

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  A portion of amino acids 1141-1166 from the human protein was used as the immunogen for this ERBB4 antibody.

• Clonality:

  Polyclonal

• Isotype:

  Ig

• Applications:

  WB, ELISA

• Purity:

  Antigen affinity

• Format:

  Antigen affinity purified

• Buffer:

  In 1X PBS, pH 7.4, with 0.09% sodium azide

• Reconstitution:

  Aliquot the ERBB4 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

• Limitations:

  This ERBB4 antibody is available for research use only.

• Storage Conditions:

  Aliquot the ERBB4 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

• Formulation:

  In 1X PBS, pH 7.4, with 0.09% sodium azide

• Applications Notes:

  Titration of the ERBB4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

• Prediction Reactivity:

  Rat

• CAS Number:

  9007-83-4

• Image Legend:

  Western blot testing of ERBB4 antibody at 1:2000 dilution + MCF-7 lysate; Predicted molecular weight: 147-180 kDa (precursor), 120, 80 kDa (cleaved forms) .