AMT-NHS

CAT: 0804-HY-150014-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-150014-01Size:5 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
AMT-NHS is an RNA-protein crosslinker. AMT-NHS is composed of a psoralen derivative and an N-hydroxysuccinimide ester group which react with RNA bases and primary amines of protein, respectively. AMT-NHS can penetrate into living yeast cells and crosslink Cbf5 to H/ACA snoRNAs with high specificity. AMT-NHS induces different crosslinking patterns and targets both single- and double-stranded regions of RNA. AMT-NHS can be used for capturing diverse RNA-protein interactions in cells[1].
CAS Number
[2925268-86-4]
UNSPSC
12352005
Target
Biochemical Assay Reagents
Type
Reference compound
Related Pathways
Others
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/amt-nhs.html
Purity
98.70
Solubility
DMSO : 25 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(ON1C(CCC1=O)=O)CCSCC2=C(C)OC(C(C)=C3O4)=C2C=C3C(C)=CC4=O
Molecular Formula
C22H21NO7S
Molecular Weight
443.47
References & Citations
[1]Han Y, et al. Development of an RNA-protein crosslinker to capture protein interactions with diverse RNA structures in cells. RNA. 2022 Mar;28 (3) :390-399.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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