Thalidomide-NH-C2-2-azaspiro[3.3]heptane

CAT:

804-HY-168312

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CAS Number: 2573305-00-5
UNSPSC Description: Thalidomide-NH-C2-2-azaspiro[3.3]heptane is a conjugate of E3 ubiquitin ligase ligand + Linker, used for the synthesis of KT-413 (HY-153368)[1].
Target Antigen: E3 Ligase Ligand-Linker Conjugates
Type: Reference compound
Related Pathways: PROTAC
Applications: Cancer-programmed cell death
Field of Research: Cancer
Assay Protocol: https://www.medchemexpress.com/thalidomide-nh-c2-2-azaspiro-3-3-heptane.html
Smiles: O=C(N1C2C(NC(CC2)=O)=O)C3=CC=CC(NCCC(C4)CC54CNC5)=C3C1=O
Molecular Weight: 396.44
References & Citations: [1]Weiss Matthew M. Preparation of benzothiazole derivatives as IRAK degraders and uses thereof. World Intellectual Property Organization, WO2021127190 A1. 2021-06-24.
Shipping Conditions: Room temperature
Clinical Information: No Development Reported

Cat	Name
HY-168312	Thalidomide-NH-C2-2-azaspiro[3.3]heptane
HY-153042	Thalidomide-NH-C2-azaspiro[3.5]nonane (hydrochloride)
HY-161190	Thalidomide-piperidine-C-2,6-diazaspiro[3.3]heptane-C2-OH
HY-130853-01	Thalidomide-NH-PEG2-C2-NH-Boc
HY-130853-02	Thalidomide-NH-PEG2-C2-NH-Boc
HY-161187	Thalidomide-piperidine-1,6-diazaspiro[3.3]heptane-boc
HY-131308	Thalidomide-NH-C2-PEG3-OH
HY-138849	Thalidomide-NH-amido-C2-NH2
HY-158343	Thalidomide-NH-PEG2-C2-CH2
HY-138857	Thalidomide-NH-amido-PEG4-C2-NH2

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