Thalidomide-NH-PEG2-C2-NH-Boc
CAT:
804-HY-130853-01
Size:
250 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Thalidomide-NH-PEG2-C2-NH-Boc
- CAS Number: 2097509-40-3
- UNSPSC Description: Thalidomide-NH-PEG2-C2-NH-Boc is a synthesized?E3 ligase ligand-linker conjugate?that incorporates the?Thalidomide?based cereblon ligand and a PEG linker used for dBRD9 (compound 6) synthesis. dBRD9 is a selective BRD9 probe PROTAC degrader for the study of BAF complex biology[1].
- Target Antigen: Apoptosis; Autophagy; E3 Ligase Ligand-Linker Conjugates
- Type: Reference compound
- Related Pathways: Apoptosis;Autophagy;PROTAC
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/thalidomide-nh-peg2-c2-nh-boc.html
- Purity: 98.37
- Solubility: DMSO : ≥ 100 mg/mL
- Smiles: O=C(OC(C)(C)C)NCCOCCOCCNC1=CC=CC(C(N2C(CC3)C(NC3=O)=O)=O)=C1C2=O
- Molecular Weight: 504.53
- References & Citations: [1]David Remillard, et al. Degradation of the BAF Complex Factor BRD9 by Heterobifunctional Ligands.2017 May 15;56(21):5738-5743.
- Shipping Conditions: Blue Ice
- Storage Conditions: -20°C (Powder, stored under nitrogen)
- Clinical Information: No Development Reported