hMAO-B/MB-COMT-IN-1

hMAO-B/MB-COMT-IN-1

• CAS Number: 254974-70-4
• UNSPSC Description: hMAO-B/MB-COMT-IN-1 is a dual MAO-B/MB-COMT inhibitor (IC50s: 2.5 μΜ for hMAO-B, 3.84 μΜ for MB-COMT). hMAO-B/MB-COMT-IN-1 protects cells against oxidative damage. hMAO-B/MB-COMT-IN-1 can be used in the research of neurodegeneration disease, such as Parkinson’s Disease (PD)[1].
• Target Antigen: COMT; Monoamine Oxidase
• Type: Reference compound
• Related Pathways: Metabolic Enzyme/Protease;Neuronal Signaling
• Applications: Neuroscience-Neurodegeneration
• Field of Research: Neurological Disease
• Assay Protocol: https://www.medchemexpress.com/hmao-b-mb-comt-in-1.html
• Solubility: DMSO : 100 mg/mL (ultrasonic)
• Smiles: OC1=C(C=CC(/C=C/C=C/C(N2CCCCC2)=O)=C1)O
• Molecular Weight: 273.33
• References & Citations: [1]Daniel Chavarria, et al. Boosting caffeic acid performance as antioxidant and monoamine oxidase B/catechol-O-methyltransferase inhibitor. Eur J Med Chem. 2022 Sep 8;243:114740.
• Shipping Conditions: Room Temperature
• Clinical Information: No Development Reported