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BSF-466895

CAT: 0804-HY-15973Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-15973Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
BSF-466895 (A-422885.66) is a Tie2 inhibitor with an IC50 of 5 nM and it can also inhibit Tie1[1][2].
CAS Number
262442-90-0
Product Name Alternative
A-422885.66
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Tie
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/bsf-466895.html
Smiles
O=S(C1=CC=CC(Cl)=C1Cl)(NC2=CC=C(C3=CN([C@H]4CC[C@H](N5CCN(C)CC5)CC4)C6=NC=NC(N)=C63)C=C2F)=O
Molecular Formula
C29H32Cl2FN7O2S
Molecular Weight
632.58
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
References & Citations
[1]Jerry Adams, et al. A strategy for the design of multiplex inhibitors for kinase-mediated signalling in angiogenesis. Curr Opin Chem Biol. 2002 Aug;6 (4) :486-92.|[2]Dieter Marmé, et al. The impact of anti-angiogenic agents on cancer therapy. J Cancer Res Clin Oncol. 2003 Nov;129 (11) :607-20.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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