Bacterial Sortase Substrate II

• Description:

  Bacterial Sortase Substrate II_x000D_ Catalog number: B2011395_x000D_ Lot number: Batch Dependent_x000D_ Expiration Date: Batch dependent_x000D_ Amount: 1 mg_x000D_ Molecular Weight or Concentration: 1472.7 g/mol_x000D_ Supplied as: Lyophilized_x000D_ Applications: molecular tool for various biochemical applications_x000D_ Storage: -20 °C_x000D_ Keywords:_x000D_ Bacterial Sortase Substrate II , Dabcyl/Edans_x000D_ Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ References:_x000D_ 1: Scott CJ, McDowell A, Martin SL, Lynas JF, Vandenbroeck K, Walker B. Irreversible inhibition of the bacterial cysteine protease-transpeptidase sortase (SrtA) by substrate-derived affinity labels Biochem J. 2002 Sep 15;366(Pt 3):953-8._x000D_ 2: Das S, Pawale VS, Dadireddy V, Singh AK, Ramakumar S, Roy RP. Structure and specificity of a new class of Ca(2+)-independent housekeeping sortase from Streptomyces avermitilis provide insights into its non-canonical substrate preference J Biol Chem. 2017 Apr 28;292(17):7244-7257._x000D_ 3: Kruger RG, Otvos B, Frankel BA, Bentley M, Dostal P, McCafferty DG. Analysis of the substrate specificity of the Staphylococcus aureus sortase transpeptidase SrtA Biochemistry. 2004 Feb 17;43(6):1541-51._x000D_ 4: Suree N, Liew CK, Villareal VA, Thieu W, Fadeev EA, Clemens JJ, Jung ME, Clubb RT. The structure of the Staphylococcus aureus sortase-substrate complex reveals how the universally conserved LPXTG sorting signal is recognized J Biol Chem. 2009 Sep 4;284(36):24465-77._x000D_ 5: Perry AM, Ton-That H, Mazmanian SK, Schneewind O. Anchoring of surface proteins to the cell wall of Staphylococcus aureus. III. Lipid II is an in vivo peptidoglycan substrate for sortase-catalyzed surface protein anchoring J Biol Chem. 2002 May 3;277(18):16241-8._x000D_ 6: Weiss JP. Molecular determinants of bacterial sensitivity and resistance to mammalian Group IIA phospholipase A2 Biochim Biophys Acta. 2015 Nov;1848(11 Pt B):3072-7._x000D_ 7: Silvius JR, Leventis R. A Novel "Prebinding" Strategy Dramatically Enhances Sortase-Mediated Coupling of Proteins to Liposomes Bioconjug Chem. 2017 Apr 19;28(4):1271-1282._x000D_ 8: Khare B, Fu ZQ, Huang IH, Ton-That H, Narayana SV. The crystal structure analysis of group B Streptococcus sortase C1: a model for the "lid" movement upon substrate binding J Mol Biol. 2011 Dec 9;414(4):563-77._x000D_ 9: Marraffini LA, Schneewind O. Anchor structure of staphylococcal surface proteins. V. Anchor structure of the sortase B substrate IsdC J Biol Chem. 2005 Apr 22;280(16):16263-71._x000D_ 10: Bentley ML, Lamb EC, McCafferty DG. Mutagenesis studies of substrate recognition and catalysis in the sortase A transpeptidase from Staphylococcus aureus J Biol Chem. 2008 May 23;283(21):14762-71. _x000D_ _x000D_ Products Related to Bacterial Sortase Substrate II can be found at Substrates

• Short Description:

  Catalog Number: B2011395 (1 mg)_x000D_ Bacterial Sortase Substrate II is a high quality C-terminal surface sorting signal with a LPXTG motif, labeled with the Dabcyl/Edans FRET pair. This product has been used as molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request._x000D_ _x000D_

• Weight:

  0.15

• Length:

  2

• Width:

  0.5

• Height :

  0.5