HDAC10-IN-2 (hydrochloride)
CAT:
804-HY-144782A-03
Size:
100 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
HDAC10-IN-2 (hydrochloride)
- UNSPSC Description: HDAC10-IN-2 hydrochloride (compound 10c) is a potent and highly selective HDAC10 inhibitor, with an IC50 of 20 nM. HDAC10-IN-2 hydrochloride modulates autophagy in aggressive FLT3-ITD positive acute myeloid leukemia cells[1].
- Target Antigen: Autophagy; HDAC
- Type: Reference compound
- Related Pathways: Autophagy;Cell Cycle/DNA Damage;Epigenetics
- Applications: Cancer-programmed cell death
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/hdac10-in-2-hydrochloride.html
- Solubility: DMSO : 100 mg/mL (ultrasonic)
- Smiles: O=C(NO)/C=C/C1CCN(CC1)CC2=CC=CC3=C2C=CC=C3.[H]Cl
- Molecular Weight: 346.85
- References & Citations: [1]Zeyen P, et al. Identification of histone deacetylase 10 (HDAC10) inhibitors that modulate autophagy in transformed cells. Eur J Med Chem. 2022 Apr 15;234:114272.
- Shipping Conditions: Room Temperature
- Clinical Information: No Development Reported