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AKR1C2/3-IN-2

CAT: 0804-HY-121656Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-121656Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
AKR1C2/3-IN-2 is a potential AKR1C3 inhibitor with selective AKR1C3 activity. AKR1C2/3-IN-2 is able to block AKR1C3-mediated testosterone (T) production and PSA induction, affecting the endocrine activity of prostate cancer cells. AKR1C2/3-IN-2 shows selectivity over other AKR1C enzymes, indicating its potential application in inhibiting drug-resistant prostate cancer. AKR1C2/3-IN-2 has no inhibitory activity against COX isomerases, further emphasizing its specificity as a prostate cancer inhibitory compound[1].
CAS Number
56600-73-8
UNSPSC
12352005
Hazard Statement
H302-H312-H332
Target
Endogenous Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/akr1c2-3-in-2.html
Smiles
O=C(C(CC)C1=CC=C2C=C(C=CC2=C1)OC)O
Molecular Formula
C15H16O3
Molecular Weight
244.29
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P363-P501
References & Citations
[1]Discovery of (R) -2- (6-Methoxynaphthalen-2-yl) butanoic Acid as a Potent and Selective Aldo-keto Reductase 1C3 Inhibitor
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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