AKR1C2/3-IN-1

AKR1C2/3-IN-1

• UNSPSC Description: AKR1C2/3-IN-1 (compound 3a) is a potent AKR1C2 and AKR1C3 inhibitor with IC50 values of 90, 50 nM, respectively. AKR1C2/3-IN-1 can be used as a radiation sensitizer and as a potentiator of chemotherapy cytotoxicity[1].
• Target Antigen: Aldose Reductase
• Type: Reference compound
• Related Pathways: Metabolic Enzyme/Protease
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/akr1c2-3-in-1.html
• Smiles: O=C(C(C1=O)=CC2=C(O1)C=C(O)C=C2)N(CC)CC
• Molecular Weight: 261.27
• References & Citations: [1]Jonnalagadda S, et al. Coumarin-based Aldo-Keto Reductase Family 1C (AKR1C) 2 and 3 Inhibitors. ChemMedChem. 2024 Jul 8:e202400081.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported