(R)-JAK2/STAT3-IN-1

(R)-JAK2/STAT3-IN-1

• CAS Number: 2485758-49-2
• UNSPSC Description: (R)-JAK2/STAT3-IN-1 is a GP130 D1 domain inhibitor with anti-tumor activity. (R)-JAK2/STAT3-IN-1 can inhibit the phosphorylation of JAK2 and STAT3. The affinity of (R)-JAK2/STAT3-IN-1 for GP130 protein is 3.8 μM. (R)-JAK2/STAT3-IN-1 effectively inhibits the viability and migration of tumor cells and promotes apoptosis[1].
• Target Antigen: Apoptosis
• Type: Reference compound
• Related Pathways: Apoptosis
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/r-jak2-stat3-in-1.html
• Smiles: NC(N1[C@H](CC(C2=CC=C(C=C2)C(F)(F)F)=N1)C(C3=C4)=CN(CC5=CC=C(C=C5)OCCN6CCCCCC6)C3=CC=C4Br)=O
• Molecular Weight: 682.57
• References & Citations: [1]Discovery of bazedoxifene analogues targeting glycoprotein 130
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported