EFNA5 (C) Antibody, Rabbit Polyclonal

Rabbit polyclonal to EFNA5. Ephrin-A5, a member of the ephrin gene family, prevents axon bundling in co-cultures of cortical neurons with astrocytes, a model of late stage nervous system development and differentiation. The EPH and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, particularly in the nervous system. EPH receptors typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are similarly divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands.

Anti Ephrin-A5 antibody, anti AL-1 antibody, anti EPH-related receptor tyrosine kinase ligand 7 antibody, anti LERK-7 antibody, anti EPLG7 antibody, anti LERK7 antibody, anti AF1 antibody

P52803

Human

C-terminal region of human EFNA5

Unconjugated

Neuroscience

100 μg/ml BSA

WB:1:1000-1:3000

Affinity purification

26

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

For research use only.

WB: The apparent protein size on WB may be different from the calculated M.W. due to modifications.Experiment Notes: Rabbit polyclonal antibodies were produced by immunizing animals with a GST-fusion protein containing the C-terminal region of human EFNA5.

WB

Rabbit