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TRIM33 (C2) Antibody, Rabbit Polyclonal

CAT: 0013-GTR18210321Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0013-GTR18210321Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Rabbit polyclonal to TRIM33.Tripartite motif-containing protein 33 (TRIM33) is a nuclear protein localized in discrete nuclear dotsresembling nuclear bodies. TRIM33 acts as an E3 ubiquitin-protein ligase, and promotes SMAD4ubiquitination, nuclear exclusion and degradation via the ubiquitin proteasome pathway. TRIM33 mayact as a transcriptional repressor of the TGF-beta/BMP signaling cascade. It is thought that TRIM33can monoubiquitinate SMAD4, which hampers its ability to form a stable complex with activatedSMAD2/3 resulting in inhibition of TGF-beta/BMP signaling cascade. TRIM33 plays a role in thecontrol of cell proliferation. Defects in TRIM33 are a cause of thyroid papillary carcinoma (TPC) .
Product Name Alternative
Anti-TRIM33 antibody, anti-E3 ubiquitinprotein ligase TRIM33 antibody, anti-Ectodermin homolog antibody, anti-RETfused gene 7 protein antibody, anti-Protein Rfg7 antibody, anti- Transcription intermediary factor 1gamma antibody, anti-TIF1gamma antibody, anti-Tripartite motifcontaining protein 33 antibody
UniProt
Q9UPN9
Reactivity
Human, Mouse
Immunogen
C-terminal region of human TRIM33
Clonality
Polyclonal
Conjugation
Unconjugated
Field of Research
Epigenetics
Dilution
WB:1:1000-1:3000
Purity
Affinity purification
Molecular Weight
123
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
WB
Host or Source
Rabbit
Preservative
0.01% NaN3

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