Human BCA-1/CXCL13 (Recombinant)

• Description:

  Human BCA-1/CXCL13_x000D_ Catalog number: B2010341_x000D_ Lot number: Batch Dependent_x000D_ Expiration Date: Batch dependent_x000D_ Volume/Weight: 10 ug_x000D_ pH: 7.4 upon reconstitution_x000D_ Supplied as: Lyophilized Powder_x000D_ Appearance: Powder_x000D_ Applications: highly pure Human BCA-1/CXCL13 expressed in E. coli. This protein acts as an efficient and selective attractant for B lymphocytes that also acts as a B cell homing chemokine._x000D_ Storage: -20C_x000D_ Keywords: rHuBCA-1/CXCL13; C-X-C motif chemokine 13; BCA1; BLC; SCYB13_x000D_ Grade: Biotechnology grade. All components are highly pure (minimum 95%). All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ References:_x000D_ 1: Steinmetz OM, Panzer U, Kneissler U, Harendza S, Lipp M, Helmchen U, Stahl_x000D_ RA. BCA-1/CXCL13 expression is associated with CXCR5-positive B-cell cluster_x000D_ formation in acute renal transplant rejection. Kidney Int. 2005_x000D_ Apr;67(4):1616-21._x000D_ _x000D_ 2: Ezzat M, El-Gammasy T, Shaheen K, Shokr E. Elevated production of serum_x000D_ B-cell-attracting chemokine-1 (BCA-1/CXCL13) is correlated with childhood-onset_x000D_ lupus disease activity, severity, and renal involvement. Lupus. 2011_x000D_ Jul;20(8):845-54._x000D_ _x000D_ 3: Hafez SS, Saad Wel S, Shedid NH. B-cell-attracting chemokine-1 (BCA-1/CXCL13)_x000D_ in systemic lupus erythematosus, its correlation to disease activity and renal_x000D_ involvement. Egypt J Immunol. 2014;21(2):23-32._x000D_ _x000D_ 4: Pranzatelli MR, Tate ED, Travelstead AL, Verhulst SJ. Chemokine/cytokine_x000D_ profiling after rituximab: reciprocal expression of BCA-1/CXCL13 and BAFF in_x000D_ childhood OMS. Cytokine. 2011 Mar;53(3):384-9._x000D_ _x000D_ 5: Shiels MS, Pfeiffer RM, Hildesheim A, Engels EA, Kemp TJ, Park JH, Katki HA,_x000D_ Koshiol J, Shelton G, Caporaso NE, Pinto LA, Chaturvedi AK. Circulating_x000D_ inflammation markers and prospective risk for lung cancer. J Natl Cancer Inst._x000D_ 2013 Dec 18;105(24):1871-80._x000D_ _x000D_ 6: Steinmetz OM, Stahl RA, Panzer U. Chemokines and B cells in renal_x000D_ inflammation and allograft rejection. Front Biosci (Schol Ed). 2009 Jun_x000D_ 1;1:13-22._x000D_ _x000D_ 7: Steinmetz OM, Lange-Hüsken F, Turner JE, Vernauer A, Helmchen U, Stahl RA,_x000D_ Thaiss F, Panzer U. Rituximab removes intrarenal B cell clusters in patients_x000D_ with renal vascular allograft rejection. Transplantation. 2007 Oct_x000D_ 15;84(7):842-50. doi: 10.1097/01.tp.0000282786.58754.2b. PMID: 17984836._x000D_ _x000D_ 8: Lechner CJ, Gantin RG, Seeger T, Sarnecka A, Portillo J, Schulz-Key H,_x000D_ Karabou PK, Helling-Giese G, Heuschkel C, Banla M, Soboslay PT. Chemokines and_x000D_ cytokines in patients with an occult Onchocerca volvulus infection. Microbes_x000D_ Infect. 2012 May;14(5):438-46._x000D_ _x000D_ 9: Barbieri F, Bajetto A, Porcile C, Pattarozzi A, Massa A, Lunardi G, Zona G,_x000D_ Dorcaratto A, Ravetti JL, Spaziante R, Schettini G, Florio T. CXC receptor and_x000D_ chemokine expression in human meningioma: SDF1/CXCR4 signaling activates ERK1/2_x000D_ and stimulates meningioma cell proliferation. Ann N Y Acad Sci. 2006_x000D_ Dec;1090:332-43._x000D_ _x000D_ 10: Meijer J, Zeelenberg IS, Sipos B, Roos E. The CXCR5 chemokine receptor is_x000D_ expressed by carcinoma cells and promotes growth of colon carcinoma in the_x000D_ liver. Cancer Res. 2006 Oct 1;66(19):9576-82._x000D_ _x000D_ Products Related to Human BCA-1/CXCL13 : Proteins

• Short Description:

  Catalog Number: B2010341 (10 ug)_x000D_ Human BCA-1/CXCL13 is a high quality research product used as highly pure Human BCA-1/CXCL13 expressed in E. coli. This protein acts as an efficient and selective attractant for B lymphocytes that also acts as a B cell homing chemokine. Custom bulk orders of this product are available upon request.

• Weight:

  0.15

• Length:

  2

• Width:

  0.5

• Height :

  0.5

• CAS Number:

  9000-83-3