IBMX (Standard)

CAT: 0804-HY-12318R-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-12318R-01Size:5 mg
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Description
IBMX (Standard) is the analytical standard of IBMX. This product is intended for research and analytical applications. IBMX is a broad-spectrum phosphodiesterase (PDE) inhibitor, with IC50s of 6.5, 26.3 and 31.7 μM for PDE3, PDE4 and PDE5, respectively.
CAS Number
[28822-58-4]
Product Name Alternative
3-Isobutyl-1-methylxanthine (Standard) ; Isobutylmethylxanthine (Standard)
UNSPSC
12352005
Target
Phosphodiesterase (PDE) ; Reference Standards
Type
Reference Standards
Related Pathways
Metabolic Enzyme/Protease; Others
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/ibmx-standard.html
Purity
99.77
Smiles
O=C(N1C)N(CC(C)C)C2=C(N=CN2)C1=O
Molecular Formula
C10H14N4O2
Molecular Weight
222.24
References & Citations
[1]Wu BN, et al. KMUP-1, a xanthine derivative, induces relaxation of guinea-pig isolated trachea: the role of the epithelium, cyclic nucleotides and K+ channels. Br J Pharmacol. 2004 Aug;142 (7) :1105-14|[2]Wei Y, et al. Angiotensin II type 2 receptor regulates ROMK-like K+ channel activity in the renal cortical collecting duct during high dietary K+ adaptation. Am J Physiol Renal Physiol. 2014 Oct 1;307 (7) :F833-43|[3]Hosseini A, et al. Differential metabolic effects of novel cilostamide analogs, methyl carbostiryl derivatives, on mouse and hyperglycemic rat. Iran J Basic Med Sci. 2012 Jul;15 (4) :916-25.|[4]Crosswhite P, et al. Inhibition of phosphodiesterase-1 attenuates cold-induced pulmonary hypertension. Hypertension. 2013 Mar;61 (3) :585-92.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, sealed storage, away from light and moisture
Scientific Category
Reference Standards

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