4-epi-Withaferin A

4-epi-Withaferin A

• CAS Number: 1214886-27-7
• UNSPSC Description: 4-epi-Withaferin A (compound 28) is the analogue of Withaferin A. 4-epi-Withaferin A enhances cytotoxicity and cytoprotective heat-shock-inducing activity (HSA). 4-epi-Withaferin A has the potential for the research of protein aggregation-associated diseases by stimulating cellular defense mechanisms[1].
• Target Antigen: Others
• Type: Natural Products
• Related Pathways: Others
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/4-epi-withaferin-a.html
• Solubility: 10 mM in DMSO
• Smiles: C[C@]12[C@@]3([C@@H](C=CC2=O)O)[C@](C[C@]4([H])[C@]1([H])CC[C@]5([C@@]4([H])CC[C@]5([H])[C@@H]([C@@]6([H])CC(C)=C(C(O6)=O)CO)C)C)([H])O3
• Molecular Weight: 470.60
• References & Citations: [1]Wijeratne EM, et al. Structure-activity relationships for withanolides as inducers of the cellular heat-shock response. J Med Chem. 2014;57(7):2851-2863.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported