4-oxo Withaferin A

CAT: 0931-T36893-01Size: 1 mgDry Ice: NoHazardous: No

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CAT#:0931-T36893-01Size:1 mg

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CAS Number

6850-30-2

Target

Others

Related Pathways

Others

Bioactivity

4-oxo Withaferin A is a derivative of the steroidal lactone withaferin A that has anticancer activity.1 It is cytotoxic to A2780 ovarian cancer cells and carboplatin-resistant A2780 (A2780/CP70) cells (IC50s = 7.3 and <1 μM, respectively) and is 4.4-fold selective for A2780 cells over non-cancerous ARPE19 cells.

Smiles

[H][C@@]12C[C@@]3([H])[C@]4([H])CC[C@]([H])([C@H](C)[C@@]5([H])CC(C)=C(CO)C(=O)O5)[C@@]4(C)CC[C@]3([H])[C@@]3(C)C(=O)C=CC(=O)[C@@]13O2 |c:37,t:17|

Molecular Formula

C28H36O6

Molecular Weight

468.59

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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Catalog	Name
MBS5785096	4-oxo Withaferin A
GTR19191973-01	4-oxo-27-TBDMS Withaferin A
MBS5824968	4-epi-Withaferin A
HY-N10353	4-Methyl withaferin A
HY-N10356	4,27-Dimethyl withaferin A
257107	Withaferin A

4-oxo Withaferin A

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