MMP12-IN-3

• UNSPSC Description:

  MMP12-IN-3 (compound 32) is a potent MMP12 inhibitor with an IC50 value of 4.9 nM. MMP12-IN-3 has the potential for the research of chronic respiratory diseases such as emphysema[1].

• Target Antigen:

  MMP

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Field of Research:

  Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/mmp12-in-3.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CC(C)CC(N(S(=O)(C1=CC=C(OC)C=C1)=O)CC2=CC=CC=C2)C(NO)=O

• Molecular Weight:

  406.50

• References & Citations:

  [1]Jeng AY, et al. Sulfonamide-based hydroxamic acids as potent inhibitors of mouse macrophage metalloelastase. Bioorg Med Chem Lett. 1998 Apr 21;8(8):897-902.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  208663-26-7