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7-Methoxytacrine

CAT: 0804-HY-W049312-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-W049312-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
7-Methoxytacrine (7-MEOTA) is an inhibitor of human acetylcholinesterase (hAChE) with an IC50 value of 10 μM, and can be used for the research of Alzheimer's disease (AD) [1].
CAS Number
5778-80-3
Product Name Alternative
7-MEOTA
UNSPSC
12352005
Hazard Statement
H301-H311-H315-H319-H331-H335-H351
Target
Cholinesterase (ChE)
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/7-methoxytacrine.html
Solubility
10 mM in DMSO
Smiles
NC1=C(CCCC2)C2=NC3=CC=C(OC)C=C31
Molecular Formula
C14H16N2O
Molecular Weight
228.29
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P361-P403+P233-P405-P501
References & Citations
[1]Spilovska K, et al. 7-Methoxytacrine-adamantylamine heterodimers as cholinesterase inhibitors in Alzheimer's disease treatment--synthesis, biological evaluation and molecular modeling studies. Molecules. 2013;18 (2) :2397-2418. Published 2013 Feb 20.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
AChE; BChE

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