Guanylin (human)

• Description :

  Guanylin (human), a 15-amino acid peptide, is an endogenous intestinal guanylate cyclase activator. Guanylin (human) is mainly found in gastrointestinal tract which regulates electrolytead water transport in intestinal and renal epithelia through cyclic GMP-dependent mechanism[1][2].

• UNSPSC :

  12352209

• Target :

  Endogenous Metabolite; Guanylate Cyclase

• Type :

  Peptides

• Related Pathways :

  GPCR/G Protein; Metabolic Enzyme/Protease

• Applications :

  Metabolism-protein/nucleotide metabolism

• Field of Research :

  Cancer; Endocrinology

• Assay Protocol :

  https://www.medchemexpress.com/guanylin-human.html

• Purity :

  99.77

• Solubility :

  DMSO : 100 mg/mL (ultrasonic)

• Smiles :

  [PGTCEICAYAACTGC(Disulfidebridge:Cys4-Cys12;Cys7-Cys15)]

• Molecular Formula :

  C58H87N15O21S4

• Molecular Weight :

  1458.66

• References & Citations :

  [1]M G Currie, et al. Guanylin: an endogenous activator of intestinal guanylate cyclase. Proc Natl Acad Sci U S A. 1992 Feb 1;89 (3) :947-51.|[2]J Bełtowski. Guanylin and related peptides. J Physiol Pharmacol. 2001 Sep;52 (3) :351-75.

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)

• Scientific Category :

  Peptides

• Clinical Information :

  No Development Reported

• CAS Number :

  [183200-12-6]