Alkaline Phosphatase Antibody

• Background:

  There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific) . The intestinal alkaline phosphatase gene encodes a digestive brush-border enzyme. This enzyme is upregulated during small intestinal epithelial cell differentiation.

• NCBI Gene ID:

  248

• Swiss Prot:

  P09923

• Accession Number:

  P09923

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This Alkaline Phosphatase (ALPI) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 274-304 amino acids from the Central region of human Alkaline Phosphatase (ALPI) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Cell Cycle, Cell Cycle, Immunology, Obesity, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  57 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  ALPI

• NCBI Official Name:

  Intestinal-type alkaline phosphatase

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  References for protein:

• Background Reference 02:

  Torres, M.I., Pathol. Res. Pract. 203 (6), 485-487 (2007)

• Background Reference 03:

  Olsen, L., Am. J. Physiol. Gastrointest. Liver Physiol. 289 (2), G220-G226 (2005)

• Background Reference 04:

  Alkhoury, F., Am. J. Physiol. Gastrointest. Liver Physiol. 289 (2), G285-G290 (2005)

• Other Product Names:

  Intestinal-type alkaline phosphatase, IAP, Intestinal alkaline phosphatase, ALPI

• Tested Applications:

  WB, IHC-P, IF

• Protein ID:

  130744

• Physical Properties:

  Liquid