IC-1k

• Description :

  IC-1k is a potent HIV-1 inhibitor with EC50 values of 2.69, 97.97 nM for HIV-1 IIIB, HIV-2 ROD, respectively. IC-1k shows cytotoxicity. IC-1k shows antiviral activity[1].

• UNSPSC :

  12352211

• Target :

  HIV

• Type :

  Reference compound

• Related Pathways :

  Anti-infection

• Applications :

  COVID-19-anti-virus

• Field of Research :

  Infection

• Assay Protocol :

  https://www.medchemexpress.com/ic-1k.html

• Smiles :

  FC1=CC(C[C@@H](C(N(C2=CC3=C(SC=N3)C=C2)C)=O)NC(CC4=CNC5=C4C=C(O)C=C5)=O)=CC(F)=C1

• Molecular Formula :

  C27H22F2N4O3S

• Molecular Weight :

  520.55

• References & Citations :

  [1]Xu S, et al. "Pseudosubstrate Envelope"/Free Energy Perturbation-Guided Design and Mechanistic Investigations of Benzothiazole HIV Capsid Modulators with High Ligand Efficiency. J Med Chem. 2024 Oct 17.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  HIV-1; HIV-2