ZW10 Interactor Recombinant Protein

• Background:

  ZW10 Interactor is localized to the kinetochores from late Prophase to Anaphase and has a uniform distribution in the cytoplasm of Interphase cells. ZWINT interacts ZW10, MIS12 and NDC80 subunit of the NDC80 complex specifically during mitosis. ZWINT is a part of the MIS12 complex which is required for kinetochore formation and spindle checkpoint activity. In addition, ZWINT is required to target ZW10 to the kinetochore at prometaphase.

• NCBI Gene ID:

  11130

• Swiss Prot:

  O95229

• Accession Number:

  O95229

• Tag:

  N-6 His tag

• Type:

  Recombinant Proteins

• Source:

  E. coli

• Field of Research:

  Cell Cycle

• Buffer:

  Lyophilized from a 0.2 um filtered solution of 20mM PB, 150mM NaCl, pH 7.2. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.

• Shipping Conditions:

  Room Temp

• Calculated Molecular Weight:

  33.4 kD

• Applications Notes:

  This recombinant protein can be used for biological assays. For research use only.

• NCBI Official Name:

  ZW10 interacting kinetochore protein

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  ZW10 Interactor, ZW10-Interacting Protein 1, Zwint-1, ZWINT

• Species:

  Human

• Physical Properties:

  Lyophilized

• CAS Number:

  9000-83-3