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CD40 Recombinant Protein

CAT: 0223-96-086Size: 0.2 mgDry Ice: NoHazardous: No
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CAT#:0223-96-086Size:0.2 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Tumor necrosis factor receptor superfamily member 5 (TNFRSF5) is also known as CD40, is a member of the TNF receptor superfamily. The expression of CD40 is diverse. TNFRSF5 has been found to be essential in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation. CD40 is the receptor for TNFSF5/CD40LG. Defects in CD40 are the cause of immunodeficiency with hyper-IgM type 3 (HIGM3) .
CAS Number
9000-83-3
NCBI Gene ID
958
Swiss Prot
P25942
Accession Number
P25942-1
Tag
C-His Tag
Type
Recombinant Proteins
Source
HEK293 cells
Field of Research
Apoptosis, Immunology, Neuroscience, Signal Transduction, Stem Cell, Other
Purity
>95% as determined by SDS-PAGE.
Buffer
PBS, pH7.4
Shipping Conditions
Room Temp
Storage Conditions
Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.
Calculated Molecular Weight
20 kDa
Applications Notes
This recombinant protein can be used for WB. For research use only.
NCBI Official Name
CD40 molecule, TNF receptor superfamily member 5
NCBI Organism
Homo sapiens
Background Reference 01
Ferrari S., et al., 2001, Proc. Natl. Acad. Sci. U.S.A. 98:12614-12619
Background Reference 02
Singh J., et al., 1998, Protein Sci. 7:1124-1135.
Other Product Names
CD40, Bp50, CDW40, MGC9013, TNFRSF5, p50
Tested Applications
WB
Species
Human
Physical Properties
Lyophilized

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