CD40 Recombinant Protein

• Background :

  Tumor necrosis factor receptor superfamily member 5 (TNFRSF5) is also known as CD40, is a member of the TNF receptor superfamily. The expression of CD40 is diverse. TNFRSF5 has been found to be essential in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation. CD40 is the receptor for TNFSF5/CD40LG. Defects in CD40 are the cause of immunodeficiency with hyper-IgM type 3 (HIGM3) .

• NCBI Gene ID :

  958

• Swiss Prot :

  P25942

• Accession Number :

  P25942-1

• Tag :

  C-His Tag

• Type :

  Recombinant Proteins

• Source :

  HEK293 cells

• Field of Research :

  Apoptosis, Immunology, Neuroscience, Signal Transduction, Stem Cell, Other

• Purity :

  >95% as determined by SDS-PAGE.

• Buffer :

  PBS, pH7.4

• Shipping Conditions :

  Room Temp

• Storage Conditions :

  Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.

• Calculated Molecular Weight :

  20 kDa

• Applications Notes :

  This recombinant protein can be used for WB. For research use only.

• NCBI Official Name :

  CD40 molecule, TNF receptor superfamily member 5

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Ferrari S., et al., 2001, Proc. Natl. Acad. Sci. U.S.A. 98:12614-12619

• Background Reference 02 :

  Singh J., et al., 1998, Protein Sci. 7:1124-1135.

• Other Product Names :

  CD40, Bp50, CDW40, MGC9013, TNFRSF5, p50

• Tested Applications :

  WB

• Species :

  Human

• Physical Properties :

  Lyophilized

• CAS Number :

  9000-83-3