TWEAK Receptor Recombinant Protein

• Background:

  Tumor necrosis factor receptor superfamily member 12A (TNFRSF12A) is also known as Fibroblast growth factor-inducible immediate-early response protein 14, FN14, CD266 antigen and tweak-receptor. TNFRSF12A is a single-pass type I membrane protein, including a 27 aa signal peptide, a 53 aa extracellular domain, a 21 aa transmembrane domain and a 28 aa cytoplasmic domain. TNFRSF12A is highly expressed in heart, placenta and kidney. TNFRSF12A can be induced by FGF1 and phorbol ester. TNFRSF12A binds to TWEAK/TNFSF12A to initiate a signal transduction cascade, causing different cellular responses such as cell death, cell proliferation, and angiogenesis.

• NCBI Gene ID:

  51330

• Swiss Prot:

  Q9NP84

• Accession Number:

  Q9NP84

• Tag:

  C-Fc tag

• Type:

  Recombinant Proteins

• Source:

  Human Cells

• Field of Research:

  Apoptosis

• Buffer:

  Lyophilized from a 0.2 um filtered solution of 20mM PB,150mM NaCl, pH7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.

• Shipping Conditions:

  Room Temp

• Calculated Molecular Weight:

  35.6 kD

• Applications Notes:

  This recombinant protein can be used for biological assays. For research use only.

• NCBI Official Name:

  Tumor necrosis factor receptor superfamily member 12A

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  TNFRSF12A, Fibroblast growth factor-inducible immediate-early response protein 14, FN14, CD266 antigen and tweak-receptor., TWEAK R

• Species:

  Human

• Protein ID:

  78070603

• Physical Properties:

  Lyophilized

• CAS Number:

  9000-83-3