CCL2 Recombinant Protein

CAT: 0223-92-670Size: 0.05 mgDry Ice: NoHazardous: No
CAT#:0223-92-670Size:0.05 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The chemokine (C-C motif) ligand 2 (CCL2), also known as monocyte chemoattractant protein (MCP) -1 and small inducible cytokine A2 (SCYA2) ), is a small cytokine that belongs to the CC chemokine family responsible for monocyte attraction. Its cognate receptor, CCR2, play a critical role in regulating nociceptive processes during neuropathic pain. Both CCL2 and CCR2 are implicated in induction of autoimmunity. CCL2 recruits monocytes, memory T cells, and dendritic cells to the sites of inflammation produced by either tissue injury or infection. Recently research also showed that CCL2 might be useful as a biomarker of fibrosis as well as a target for therapeutic intervention.
CAS Number
9000-83-3
NCBI Gene ID
29126
Swiss Prot
Q9NZQ7
Accession Number
Q9NZQ7
Tag
Tag Free
Type
Recombinant Proteins
Source
E. coli
Field of Research
Apoptosis, Cancer, Cell Cycle, Immunology
Buffer
Lyophilized from a 0.2 um filtered solution of 20mM PB, 150mM NaCl, pH7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.
Shipping Conditions
Room Temp
Calculated Molecular Weight
8.7 kD
Applications Notes
This recombinant protein can be used for biological assays. For research use only.
NCBI Official Name
CD274 molecule
NCBI Organism
Homo sapiens
Other Product Names
C-C motif chemokine 2, HC11, Monocyte chemoattractant protein 1, Monocyte chemotactic and activating factor, MCAF, Monocyte chemotactic protein 1, MCP-1, Monocyte secretory protein JE, Small-inducible cytokine A2, CCL2
Species
Human
Physical Properties
Lyophilized

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