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MAPT-F Recombinant Protein

CAT: 0223-92-239Size: 0.05 mgDry Ice: NoHazardous: No
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CAT#:0223-92-239Size:0.05 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Tau proteins are proteins which contain four Tau/MAP repeats. They promote microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. They are abundant in neurons of the central nervous system and are less common elsewhere, but are also expressed at very low levels in CNS astrocytes and oligodendrocytes. The tau proteins are the product of alternative splicing from a single gene that in humans is designated MAPT. When tau proteins are defective, and no longer stabilize microtubules properly, they can result in several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy.
CAS Number
9000-83-3
NCBI Gene ID
4137
Swiss Prot
P10636-8
Accession Number
P10636-8
Tag
Tag Free
Type
Recombinant Proteins
Source
E. coli
Field of Research
Neuroscience, Other
Buffer
Lyophilized from a 0.2 um filtered solution of PBS, pH 7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.
Shipping Conditions
Room Temp
Calculated Molecular Weight
45.85 kD
Applications Notes
This recombinant protein can be used for biological assays. For research use only.
NCBI Official Name
Microtubule associated protein tau
NCBI Organism
Homo sapiens
Other Product Names
Microtubule-associated protein tau, MAPTL, Neurofibrillary tangle protein, MTBT1, Paired helical filament-tau, TAU and MAPT; , Tau-F
Species
Human
Physical Properties
Lyophilized

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